Enoxaparin is a medication that is primarily used to help reduce the risk for intra-vascular (in blood vessels) clot formation secondary to other systemic illness.  Enoxaparin is a low-molecular weight heparin and works to inhibit the body’s natural clotting mechanisms.  In doing so, cats and dogs with certain types of heart disease or endocrine disease, which may predispose to clot formation (i.e. hypertrophic cardiomyopathy, immune-mediated hemolytic anemia, Cushing’s disease, renal disease, or chronic inflammatory bowel disease) are protected from the adverse effects associated with obstruction to blood flow from clot formation.  Intra-vascular clot formation may result in everything from no symptoms to complete paralysis of the hind limbs, renal failure, seizures, etc.  This medication is typically provided in a pre-dosed syringe intended for human administration, however due to the small size of veterinary patients, it often must be injected into a separate small sterile vial for smaller sampling using an insulin syringe and given as an injection under the skin.  Side-effects of this medication are rare in animals, and may include excessive bruising tendencies in animals with hair thinning.  Overdoses may result in excessive bleeding such as bleeding from the nose, urinary tract, or gastrointestinal tract, and if these are identified, consultation with a veterinarian is recommended.

Enoxaparin Preparation

1. Remove Exoxaparin syringe from packaging.

2. Remove the plastic lid from the empty sterile vial.

3. Firmly hold the sides of the syringe and remove the plastic needle cover.

4. Push the needle completely though the center rubber on top of vial.

5. Fully depress the plunger on the syringe emptying the entire contents into the bottle.